Mentioned:
GLP-1s have quickly become one the single most successful pharmaceutical products ever. And now, they might be causing a new boom in medical aesthetics.
What’s happening:
- Multiple private and public companies have been investing in clinical research and new product development targeting the aesthetic effects caused by GLP-1 induced rapid weight loss
Why it matters:
- McKinsey publicly stated in a research report that 63% of patients seeking facial aesthetics after GLP-1 weight loss were not previously active users of medical aesthetic treatments
Who is making moves:
- South Korea’s L&C Bio is developing an injectable product known as MegaAdipoECM which is aiming to provide a biological scaffold into which the patient’s own cells can migrate into and repopulate the area to deal with facial volume loss and skin laxity from GLP-1 weight loss
- Rapalogix Health raised a $20M USD Series A financing round to advance their skincare line and complete Investigation New Drug work for their aesthetic dermatology drug RLX-202
- Pharmaceutical giant Galderma has made GLP-1 facial volume loss a meaningful research priority over the last year and a half and Chief Executive Officer Flemming Ornskov publicly stated that GLP-1 patients have started to provide an early boost to their aesthetics and injectables business
- Conexeu Sciences (NASDAQ: CNXU) has publicly stated they are aiming to position their proprietary CXU platform for medical aesthetics and facial and body tissue restoration
Going deeper:
- Conexeu Sciences just recently made waves when they successfully completed their 12 month preclinical study focused on evaluating their CXU platform as a potential tissue restoration solution for medical aesthetics and the knock on effects caused by GLP-1 weight loss drugs
- The 12 month preclinical trial completed completed by Conexeu Sciences demonstrated that their CXU platform met its objective for tissue restoration in a facial model and is designed to be delivered through a fine-gauge needle for precise placement to support the tissue changes that can follow GLP-1 weight loss, including both facial volume loss as well as skin laxity
The intrigue:
- The United States Food and Drug Administration has notably given Conexeu Sciences pre-submission feedback for their initial wound care indication


